Experimental study on the optimization of extraction process of garlic oil and its antibacterial effects.
نویسنده
چکیده
BACKGROUND Garlic oil which is the main active constituent of garlic has a wide range of pharmacological activities, and a broad antibacterial spectrum. It also has a strong anti-cancer activity, and can significantly inhibit a variety of tumors such as liver cancer, gastric cancer and colon cancer. The objective is to study the extraction process of garlic oil and its antibacterial effects. MATERIALS AND METHODS CO2 Supercritical extraction was used to investigate the optimal processing conditions for garlic oil extraction; filter paper test and suspension dilution test were applied to determine the bacteriostatic action of garlic oil. RESULTS In the CO2 supercritical extraction experiment, factors influencing the yield of garlic oil were: extraction pressure > extraction temperature > extraction time in descending order. Range analysis showed that the optimal experimental conditions for CO2 supercritical extraction of garlic oil were extraction pressure of 15 Mpa, temperature of 40 °C, and duration of 1 h. Different concentrations of garlic oil could all inhibit the growth of Staphylococcus aureus, Escherichia coli and Bacillus subtilis, suggesting that garlic oil has an antibacterial effect. CONCLUSION The optimal experimental conditions for CO2 supercritical extraction of garlic oil were: extraction pressure of 15 Mpa, temperature of 40 °C, and duration of 1 h; garlic oil has an antibacterial effect.
منابع مشابه
Optimization of ultrasonic-assisted extraction of sesame oil
Background & Aim: Sesame is one of the oldest cultivated plants in the world and is one of the oldest oily products used by humans. Sesame oil is an important industrial, oral and medicinal oil. Today, the use of ultrasound has grown significantly due to its effects on food storage and processing. Experimental: In this research, the response level model w...
متن کاملOptimization of ultrasonic-assisted extraction of sesame oil
Background & Aim: Sesame is one of the oldest cultivated plants in the world and is one of the oldest oily products used by humans. Sesame oil is an important industrial, oral and medicinal oil. Today, the use of ultrasound has grown significantly due to its effects on food storage and processing. Experimental: In this research, the response level model w...
متن کاملAntibacterial Activity of Elephant Garlic and Its Effect against U2OS Human Osteosarcoma Cells
Objective(s): The present study was designed to investigate the antibacterial function and pharmacological effect of elephant garlic (Allium ampeloprasum var. ampeloprasum) on U2OS human osteosarcoma cells. Materials and Methods: Seven kinds of bacteria were reconstituted, inoculated and tested in this research to evaluate elephant garlic antibacterial activity. By the means ...
متن کاملPhysicochemical Characteristics of Nanoliposome Garlic (Allium sativum L.) Essential Oil and Its Antibacterial Effect on Escherichia coli O157:H7
Background: Escherichia coli O157:H7 is a Gram-negative and facultative anaerobic food-borne bacterial pathogen. The major purpose of this study was to evaluate physicochemical characteristics of nanoliposome garlic Essential Oil (EO) and its antibacterial effect on E. coli O157:H7. Methods: Nanoliposome garlic EO was prepared by ethanol injection method and its physicochemical properties were...
متن کاملApplication of the Response Surface Methodology for the Optimization of the Aqueous Enzymatic Extraction of Pistacia Khinjuk Oil
ABSTRACT: Aqueous enzymatic extraction of oil from pistacia khinjuk was performed using cellulase. The central composite design was used to optimize the parameters that are significant to the process. The influence of three regressors on the percentage of oil recovery from seed was evaluated using second-order polynomial multiple regression model. Analysis of variance showed a high coefficient ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- African journal of traditional, complementary, and alternative medicines : AJTCAM
دوره 11 2 شماره
صفحات -
تاریخ انتشار 2014